Midodrine or Midodrine HCL is a vasopressor, a medication used to regulate the body’s blood pressure. It constricts the blood arteries in the body to increase blood pressure.
Midodrine treats low blood pressure, often known as hypotension, which can cause severe convulsions and disorientation. However, it has little effect on the capacity to carry out daily tasks.
Caution in Use
- Midodrine should be used with caution in patients with overactive thyroid, serious heart illness, an adrenal gland tumour, kidney disease, or an abnormal urine pattern.
- Midodrine may elevate blood pressure while the patient is resting. Therefore, the medication should only be taken when the blood pressure is so low that it interferes with everyday living. The medication moderates the individual’s blood pressure, allowing them to live everyday life.
- Before commencing treatment with Midodrine, it is crucial to inform your doctor if you have a history of liver or renal illness, Diabetes, glaucoma, or any other serious condition. Pregnant and breastfeeding women should only use the medicine on the advice of a physician; otherwise, they should avoid it.
Administration
- Midodrine should be administered as prescribed by a physician. It is recommended three times daily, with a 3-hour delay between doses. The final dose of the day should be taken at least three to four hours before night to prevent a rapid increase in blood pressure. Preferably, the medication should be administered during typical waking hours when the body is active.
- The medication may be administered with or without meals. When taking medicine, the blood pressure, kidney, and liver functions should be monitored routinely to identify any abnormalities that may emerge during therapy.
- It should be kept at room temperature and away from heat and moisture.
An overdose of Midodrine is accompanied by symptoms such as rapid pulse, blurred vision, extreme flushing, excessive urine, and feeling chilly and restless. Immediate contact a medical professional in case of an overdose.
Side Effects
Midodrine’s most frequent and common side effects include the following:
- An excessively slowed heart rate.
- Allergic responses.
- Oedema of the face and mouth region.
Symptoms such as dizziness, a weak pulse, a pounding sensation in the ear, blurred vision, buzzing in the ears, anxiety, increased or painful urination, chest discomfort, irregular heartbeats, or a seizure may be observed in some instances. Seek immediate medical attention when severe side effects are observed.
In conclusion, Midodrine is an alpha-adrenergic medication that causes constriction of blood vessels and elevation of blood pressure by activating particular receptors. It is utilised to treat low blood pressure.
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Disclaimer:
Shubham Pharmachem’s blog posts have been written with the information gathered from approved medical journals and websites online. Our research and technical teams strive to provide relevant information through such articles. We strongly advise readers not to consume or administer medication without prior consultation with their doctor.
References:
- https://www.1mg.com/generics/midodrine-405198
- https://www.drugs.com/mtm/midodrine.html
